2008; 2: ISSUE 5
New Drugs in Hematology

Bologna, Italy, 5-7 OCTOBER 2008

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SESSION I

Myelodysplastic syndromes
M. Cazzola

Organ damage and iron overload
E. Angelucci, C. Cogoni, M. Pettinau, F. Pilo, C. Targhetta, F. Zacchedu

Progress in the management of iron overload in erytrocyte disorders
M.D. Cappellini, E. Cassinerio, L. Zanaboni, G. Fabio, P. Pattoneri

 

SESSION II

Ph Positive-Leukemias
F. Guilhot, L. Roy, J. Guilhot, P-J. Saulnier, J-M. Gombert, A. Turhan

Thyrosin kinase inhibitors: nilotinib
F. Castagnetti, F. Palandri, G. Gugliotta, A. Poerio, M. Amabile, S. Soverini, G. Martinelli,
M. Baccarani, G. Rosti

New drugs to overcome meccanisms of resistance in Ph+ leukemia: bosutinib
G. Martinelli, I. Iacobucci, D. Cilloni, P. Giannoulia, S. Soverini, P.P. Piccaluga,
C. Papayannidis, S. Paolini, C. Terragna, M. Amabile, S. Colarossi, A. Gnani, F. Pane,
G. Saglio, M. Baccarani

 

SESSION III

Peripheral T-cell lymphomas
S.A. Pileri, C. Agostinelli, C. Campidelli, F. Bacci, E. Sabattini, A. Pileri jr, P.P. Piccaluga

Histone deacetylase inhibitors: saha (Vorinostat).
A treatment option for advanced cutaneous T-cell lymphoma

M. Duvic

A Phase II international, multicenter study of oral panobinostat (LBH589)
in patients with refractory cutaneous T-cell Lymphoma

M.G. Bernengo, F. Vanaclocha, M. Duvic, T. Kuzel, F. Kerdel, L. Pinter-Brown, A. Bosly,
C. Okada, D. Breneman, P.L. Zinzani, J. Becker, L. Hughey, M. Ardaiz, J. Zain, L. Zhang,
S. Hirawat, G. Laird, D. Johnson, H.M. Prince

SESSION IV

Chronic lymphocytic leukemia
F. Caligaris-Cappio

Monoclonal antibodies (update): cd20, rituximab
A. Hagenbeek

90Y-ibritumumab tiuxetan (Zevalin)
P.L. Zinzani

Update of alemtuzumab in the treatment of chronic lymphocytic leukaemia
C. Dearden

Immunotherapy with epratuzumab in B-cell non-Hodgkin’s lymphoma
P. Martin, D. Goldenberg, J.P. Leonard

New agents for the treatment of acute myeloid leukemia: gemtuzumab ozogamicin
S. Amadori

 

SESSION V

Update on galiximab: anti-cd80 monoclonal antibody
M.S. Czuczman

CMC-544 (inotuzumab ozogamicin): a CD-22-targeted immunoconjugate
of calicheamicin

J.F. DiJoseph, K. Khandke, M.M. Dougher, D.Y. Evans, D.C. Armellino,
P.R. Hamann, N.K. Damle

Zanolimumab (HuMax-CD4®), a fully human monoclonal antibody in
clinical development for cutaneous T-cell lymphoma

C. Assaf

Monoclonal antibodies (novel): humax-cd20, ofatumumab
A. Hagenbeek

Lumiliximab in chronic lymphocytic leukemia
T.S. Lin

Bevacizumab as an anti-vegf strategy in lymphoma
S.J. Horning

HuMax-CD38, a new human CD38 monoclonal antibody, effectively mediates killing
of multiple myeloma and plasma cell leukemia cells

P.W.H.I. Parren

 

SESSION VI

Individualizing therapy for the hematologic malignancies: the stuff of genes and dreams
B.D. Cheson

Aurora kinase inhibitor: AS703569
A. Gianella-Borradori

Pha-739358: a pan-aurora kinase inhibitor
R. Paquette, N. Shah, C. Sawyers, G. Martinelli, J. Nicoll, M. Chalukya, G. Locatelli, L. Capolongo, J. Moll, S. Comis, B. Laffranchi

 

SESSION VII

From cell biology to therapy: lenalidomide in untreated multiple myeloma
A. Palumbo, P. Falco, F. Gay, V. Magarotto, F. Patriarca, C. Nozzoli, M. Boccadoro

From cell biology to therapy: lenalidomide in relapsed/refractory multiple myeloma
P. Richardson, T. Hideshima, C. Mitsiades, R. Schlossman, J. Laubach, I. Ghobrial, N. Raje,
N. Munshi, K. Anderson

From cell biology to therapy: forodesine
M. Duvic

Flavopiridol (alvocidib) in chronic lymphocytic leukemia
T.S. Lin, B. Fischer, K.A. Blum, M. Brooker-McEldowney, M.E. Moran, L.A. Andritsos, J.M. Flynn, M.A. Phelps, J.T. Dalton, A.J. Johnson, S.M. Mitchell, L.L. Smith, A.J. Wagner, C.A. Raymond, A.D. Colevas, M.R. Grever, J.C. Byrd 112

mTOR inhibitors for the treatment of lymphoma
T.E. Witzig

Bendamustine is a hybrid antimetabolite and alkylating agent offering
new therapeutic options for the treatment of non-Hodgkin’s lymphomas

M. Dreyling

 

SESSION VIII

Multiple myeloma
J. San Miguel

Proteasome inhibitors: bortezomib in multiple myeloma
M. Cavo, M.C. Pallotti, L. Pantani, A. Petrucci, A. Brioli, C. Terragna, N. Testoni, G. Marzocchi, S. Durante, G. Perrone, P. Tacchetti, E. Zamagni, P. Tosi, M. Baccarani


Bortezomib in lymphomas

A. Goy

Proteasome inhibitors: beyond nfkb inhibition alone and the emerging role
of combination therapy in the treatment of multiple myeloma

P. Richardson, C. Mitsiades, J. Laubach, C. Conant, T. Hideshima, D. Chauhan, R. Schlossman, I. Ghobrial, N. Munshi, K.C. Anderson

Novel proteasome inhibitors
P. Tosi, M.C. Pallotti, L. Pantani, A. Petrucci

 

SESSION IX

Decitabine in myeloid malignancies
H.I. Saba

Tipifarnib in hematologic malignancies
J-L. Harousseau

 

SESSION X

Is there a role for immunotherapy in Hodgkin’s disease?
B. Böll, A. Engert

New agents for the treatment of acute myeloid leukemia: midostaurin
S. Amadori

Lestaurtinib as a FLT3 Inhibitor
A.K. Burnett

 

 

©2006 Ferrata Storti Foundation