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Management of complications: infections, autoimmunity, cytopenias
Fausto Rossini
Haematology and Bone Marrow Transplantation Unit. University of Milan Bicocca
S. Gerardo Hospital Monza, Italy
In untreated patients or in patients treated with alkylating agents, most infections are bacterial (Haemophilus influenzae, Klebsiella pneumoniae Staphylococcus aureus, Streptococcus pneumoniae and Escherichia coli). Respiratory tract is the most frequent site of infection. Fungal and viral infections are rare and generally occur in heavily pre-treated patients; hypogammaglobulinemia and treatment-related neutropenia play a major role.
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